What Is Angelman Syndrome? Colin Farrell Opens Up About Son James' Struggle With Rare Health Condition

Irish actor Colin Farrell recently shared an update about his 20-year-old son James, who was born with Angelman Syndrome, a rare genetic condition that affects his ability to speak. James is Farrell's child with his ex-partner, model Kim Bordenave.

In an interview with People magazine, Farrell mentioned that his son is approaching 21 and having this syndrome will make it challenging for him to integrate into society.

Farrell, who shared details about his and ex-partner Kim Bordenave’s 21-year-old son to promote his new foundation aimed at supporting people with intellectual disabilities, revealed that James was initially diagnosed with cerebral palsy at age 1 and also had many symptoms similar to Angelman syndrome.

“As a toddler, James was really checked out due to his inability to sit up or crawl,” said Farrell. He received an accurate diagnosis of the rare neurogenetic disorder when he was 2. Farrell affirmed that James and other individuals like him deserve greater individuality, autonomy in their lives, and a stronger sense of community.

“I want the world to be kind with James. I want the world to treat him with kindness and respect,” Farrell added. 

What is Angelman Syndrome?

Angelman syndrome is an uncommon and intricate neurodevelopmental disorder that predominantly impacts the nervous system. It arises from abnormalities in a specific gene known as UBE3A.

The nervous system acts as your body's control centre, stemming from the brain and regulates your movements, thoughts, behaviours, and automatic reactions to your environment. Although Angelman syndrome is rare, it can occur in any fetus. Most cases are due to a spontaneous gene mutation, indicating that the condition is not inherited from biological parents. It affects both males and females equally. 

There is no cure for Angelman syndrome at present. Research is exploring treatments aimed at specific genes. Currently, treatment is centred on managing symptoms and addressing developmental delays in children affected by Angelman syndrome.